Found 31 matching trials
Elective Umbilical Hernia Repair in Patients With Cirrhosis NA Liver cirrhosis is a frequent and severe chronic disease. About 20 % of pat...
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Appropriateness of Frozen Plasma Use in Canada N/A There is little evidence to guide the current use of Frozen Plasma. Despite...
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Multiple Locations
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Trial of PCC Versus FFP in Patients Undergoing Heart Surgery PHASE2 The PROPHESY trial is a single centre pilot trial investigating Fresh Froze...
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St Bartholomew's Hospital
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Factor Replacement in Surgery PHASE2 This is a multicentre, randomized, active-control, pragmatic, Phase 2 pilot...
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Sunnybrook Health Science Centre
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Coagulation in Cirrhosis PHASE4 Out of fear of bleeding, liver cirrhosis patients are often treated prophyl...
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General Hospital of the Medical University of Vienna
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Efficacy and Safety of 4F-PCC (4-Factor Prothrombin Complex Concentrate) in Adult Patients Undergoing Complex Cardiovascular Surgery With Cardiopulmonary Bypass (CPB) PHASE3 This is a phase 3, multicenter, randomized, open-label, parallel-group, con...
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UCLA Health - Ronald Reagan Medical Center
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Patient Blood Management for Massive Obstetric Hemorrhage NA Obstetric Hemorrhage continues to be the first cause of maternal morbidity ...
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Hospital de Especialidades Del Niño Y La Mujer
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Dose-Response in PD and Safety of Cofact Under VKA Anticoagulation PHASE1 This is a randomized, open label, placebo-controlled, parallel design, sing...
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PRA Health Sciences
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Fixed-dose Activated Versus Variable-dose Inactivated Prothrombin Complex Concentrate for Warfarin-associated Major Bleed N/A This study aims to assess a fixed-dose regimen of activated prothrombin com...
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Multiple Locations
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Study of Octaplex, a Four-factor Prothrombin Complex Concentrate (4F-PCC) and Beriplex® P/N (Kcentra) for the Reversal of Vitamin K Antagonist (VKA) Induced Anticoagulation in Patients Needing Urgent Surgery With Significant Bleeding Risk. PHASE3 To demonstrate that the efficacy of OCTAPLEX as a reversal agent in patient...
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Octapharma Research Site
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